Eyedrops for Glaucoma

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Q BioMed Inc. Provides Important Update on Mannin Research Tie2 Technology Platform Development

Q BioMed Inc. (OTCQB: QBIO), a commercial stage biotechnology acceleration development company, provides the following update on its exclusively licensed platform technology asset from Mannin Research Inc.

Together with Mannin Research, the company has made significant progress on their Tie2 activating molecule – currently being optimized for a topical eye drop for the treatment of open angle glaucoma. They recently filed patents with the United States Patent and Trademark Office disclosing novel compounds capable of activating Tie2 receptor-mediated signaling. This is a tremendous achievement and involved significant and detailed work, giving them broad coverage of the platform from an intellectual property standpoint.

They have also completed initial proof-of-concept work on a novel biologic targeting Tie2 (MAN-11). This project provides them a completely different approach – i.e. a biologic vs. a small molecule, from which to build a biologic-based therapeutic platform targeting Tie2 receptor for the treatment of glaucoma and other vascular diseases.

The MAN-01 Program for primary open angle glaucoma is progressing well. Q BioMed Inc. iteratively optimized and refined new compounds for use in treating Primary Open Angle Glaucoma as an eye-drop.

The patients with primary open angle glaucoma, and their physicians, are seeking new medications to treat glaucoma, by slowing down or stopping the progressive loss of vision. There is a long standing, and demonstrated need to increase both adherence and compliance in new glaucoma therapeutics (Glaucoma Today, August 2006). Their MAN-01 program is designed to address both issues by employing improved drug delivery profiles. The company will continue optimization of its lead candidates for planned phase I clinical trials in 2019.

Mannin Research representatives and CSO, Dr. Susan Quaggin will attend the International Vascular Biology Meeting 2018 (IVBM 2018), organized in Helsinki, FinlandJune 3-7, 2018, by the European Vascular Biology Organisation, University of Helsinki & Wihuri Research Institute. The IVBM2018 will bring together researchers, executives, and investigators from all fields of vascular biology for the exchange of new ideas and discussions of burning issues. Dr. Quaggin will be presenting during the first Plenary session on June 3 discussing: ‘Stolen identities – new vascular phenotypes Tie’d to disease’.

Q BioMed and Mannin representatives are also attending The BIO International Convention (BIO 2018) on June 4-7, 2018 in Boston, MA. The BIO International Convention is hosted by the Biotechnology Innovation Organization (BIO). The key benefits of attending the 2018 BIO International Convention are access to global biotech and pharma leaders via BIO One-on-One Partnering, exposure to industry thought-leaders with over 500 education sessions, and unparalleled networking opportunities with 16,000+ attendees from 74 countries.

BIO 2018 will provide Mannin Research with the opportunity to connect with key industry partners, develop new relationships, and continue discussions with key pharmaceutical and biotechnology partners with specific expertise in commercializing novel therapeutics for ophthalmology, glaucoma, and vascular diseases. The goal is to identify and engage with partners to explore research partnerships, or commercial partnership to drive new therapeutics for treating patients with primary open angle glaucoma.

Please visit http://www.qbiomed.com and http://www.mannin.ca for more information.

About Q BioMed Inc.

Q BioMed, Inc. is a biomedical acceleration and development company. We are focused on licensing and acquiring biomedical assets across the healthcare spectrum. Q BioMed is dedicated to providing these target assets the strategic resources, developmental support and expansion capital they need to meet their developmental potential so that they can provide products to patients in need.

Please visit http://www.qbiomed.com and sign up to receive regular updates. Follow us on social media @QBioMed.

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